People taking trazodone should be aware of this and continue taking the drug as directed even if they do not see immediate improvement.
As with any antidepressant, trazodone must be carefully adjusted by the physician to produce the desired therapeutic effect.
The most common problem with trazodone is sedation (drowsiness, lack of mental and physical alertness).
This side effect is especially noticeable early in therapy.
The therapeutic effects of trazodone, like other antidepressants, appear slowly.
Maximum benefit is often not evident for at least two weeks after starting the drug.
It should be noted, however, that trazodone has not received official approval from the United States Food and Drug Administration (FDA) for these secondary uses.
Trazodone may increase heart rate and stress on the heart.In extreme cases, patients may require treatment with bethanechol, a drug that reverses this particular side effect.